2024
November
Congratulations to Zena, Anna, and Julia for their publication in Nature Communications on the discovery and characterization of the HuSH2 complex!
October
Congratulations to Aayushi Jain for successfully defending her PhD thesis!
June
Congratulations to Truman Do for successfully defending his PhD thesis! Now back to medical school to finish his MD.
Welcome to Joanne Du as a Laboratory Research Intern!
May
Congratulations to Ryen Hazzard and Rebecca Wright upon their graduation from UW-Madison! Good luck to Ryen in medical school and to Rebecca in graduate school.
2023
August
Welcome to Alireza Paniri as a new graduate student from the Genetics program.
July
Peter is awarded a H.I. Romnes Faculty Fellowship from UW-Madison!
Congratulations to Justin Mabin for successfully defending his PhD thesis! Justin will join Bobby Hogg’s lab at NIH for his postdoctoral training. Best of luck, Justin!
Congratulations to Zena Jensvold for successfully defending her PhD thesis! Zena will join Aaron Nile’s lab at Calico as a staff scientist. Best of luck, Zena!
June
Peter is awarded the inaugural Hanns Kuttner professorship from UW-Madison!
May
Congratulations to Sam Krabbehoft for successfully defending his PhD thesis! Now back to medical school to finish his MD.
2022
July
Good luck to Anna Christenson as she begins her graduate studies at UC-Berkeley!
June
Congratulations to the lab for a new R01 grant from the National Cancer Institute to study PRC2 regulation in human gliomas!
2021
July
Congratulations to Justin Mabin and the team on their publication in RNA on characterizing the snRNA gene variants in humans!
Congratulations to Tyler Reich on his 1-percentile NIH F30 fellowship on defining the role of Polycomb Repressive Complex 2 complexes in diffuse midline gliomas!
May
Congratulations to the lab for being awarded an Innovation Grant from Alex’s Lemonade Stand Foundation for Childhood Cancer!
March
Anna Christenson is awarded the Mary Shrine Peterson Undergraduate award and Hilldale Scholar Award. Congratulations, Anna!
Siddhant Jain is awarded the 2020 Raymond L. Erikson Exceptional Thesis Award! Congratulations, Sid!
February
Congratulations to Sam Krabbenhoft on receiving his NIH F30 fellowship on using Drosophila to identify of glioma driver genes. Sam is jointly mentored by the Harrison and Lewis labs.
2020
October
Congratulations to Sid, Truman and Andrew for their publication in Molecular Cell on our new insights into the mechanism of PRC2 inhibition by EZHIP and H3 K27M!
Congratulations to Sid and our collaborators on their publication in PNAS on the mechanism of the H3.3-specific G34 oncohistone mutations!
Congratulations to the lab for the competitive renewal of the P01 grant from the National Cancer Institute to study oncohistones mutations!
August
Congratulations to Sid Jain for successfully defending his thesis!
May
Congratulations to Keran Han and Anna Christenson for receiving Sophomore Research Awards!
Congratulations to the lab for new funding from the Rally Foundation for Childhood Cancer Research and from the Childhood Brain Tumor Foundation.
2019
July
Peter Lewis is awarded tenure! Congratulations, Peter!
We are excited to welcome Tyler Reich in the Lewis lab from the Medical Scientist Training Program. Tyler joins the lab after completing 2 years of his medical training.
May
Congratulations to Sid, Truman and Andrew for the new paper in Nature Communications. Along with the collaborators, the team characterizes the biochemical function of a novel oncogene EZHIP, which mimics the H3K27M oncohistone sequence to inhibit PRC2. Their work is highlighted in Nature News and View!
April
Congratulations to Zena for receiving a fellowship from National Science Foundation for her doctoral studies!
March
Mary is awarded the Mary Shrine Peterson Undergraduate award and Hilldale Scholar Award. Congratulations, Mary!
2018
December
Congratulations to Dominik Hoelper for successfully defending his thesis! Dominik is off to the Robin Allshire lab at the University of Edinburgh for his postdoctoral training. Best of luck, Dominik!
Andrew Rashoff joins the Lewis lab from the Genetics Program. We are excited to have you in the lab, Andrew!
September
We are excited to welcome Truman Do in the Lewis lab from the Medical Scientist Training Program. Truman joins the lab after completing 2 years of his medical training.
January
Congratulations to Peter for being named a Ride Scholar by The Ride Bicycle Benefit for Cancer Research!
2017
December
Zena Jensvold joins the lab as a graduate student from the Cellular and Molecular Biology program. Welcome, Zena!
October
Congratulations to Dominik and Aayushi for the publication in Nature Communications! In collaboration with Dr. Dinshaw Patel’s lab, the team identifies an ATRX-independent complex of DAXX, which is responsible for maintaining ERV silencing independent of histone H3.3 deposition.
August
Welcome, Greg Mozes and Luke Moyer to the Lewis lab as undergraduate researchers!
Nicole Neuser joins the lab as a summer research scholar from the German Academic Exchange Program (DAAD). Welcome Nicole!
January
We are excited to welcome Mary Donoghue to the Lewis lab as an undergraduate researcher.
2016
June
Peter Lewis received the Pew Scholar award in the biomedical sciences by the Pew Charitable Trusts. Congratulations, Peter!
May
Congratulations to Dan Hanna and Suma Samudrala for graduating with B.S. degrees in Biology and Molecular Biology! They are both off to Medical school at UW-Milwaukee. Best of luck!
Congratulations to Sid, Dominik and Stefan for publication of the H3K36M story in Science! Our team finds that H3K36M oncohistones drive sarcomas by genome-wide redistribution of PRC2. Check out the coverage of this story in Wisconsin News.
Congratulations to Dominik, Sid and Stefan for publication of the K-to-M mutations story in PNAS! In this collaborative study, our team solves the co-crystal structure of G9a bound to H3K9M peptide and finds that s-adenosylmethionine is necessary for inhibition of histone methyltransferases by corresponding oncohistone mutations.
2015
December
We are excited to welcome Aayushi Jain as a graduate student from the IPiB program! Aayushi joins the lab after receiving her B.S. and Masters degrees from IIT-Delhi.
Brianna Murphy joins the lab as an undergraduate researcher. Welcome, Bri!
July
The lab receives the Program Grant for studying oncohistone mutations from National Cancer Institute. Congrats, lab!
Welcome, Melanie Schwerdtfeger as a summer research student through the German Academic Exchange Program (DAAD)!
Congratulations to Dominik Hoelper for winning the best poster award at the EMBO Conference on Chromatin and Epigenetics!
June
Peter Lewis is named a Kimmel Scholar of the Sidney Kimmel Foundation for Cancer Research. Congratulations!
May
Stefan Lundgren graduates with a BS in Biochemistry! Stefan joins the lab as a Research Assistant. Welcome Stefan!
Congratulations to Dan Hanna and Suma Samudrala foe receiving Hilldale Fellowships!
Peter Lewis wins Shaw Scientist Award from the Greater Milwaukee Foundation. Congratulations, Peter!
2014
December
Ellie Glynn joins the lab as an undergraduate researcher. Welcome, Ellie!
October
JACS paper on the H3 K27M mechanism is published! The team identifies that post-translational modifications on histone tails that are refractory for PRC2 binding might “detoxify” the PRC2 inhibitory potential of H3K27M oncohistones.
June
Manlu Liu and Ellie Degen join the lab for a summer research program through the Madison Metropolitan School District.
May
Dominik Hoelper is awarded a Boehringer Ingelheim Fonds Predoctoral fellowship. Congratulations, Dominik!
Dan Hanna joins the lab as an undergraduate researcher.
January
Stefan Lundgren joins the lab as an undergraduate researcher.
2013
December
Siddhant Jain joins the lab as a graduate student through the CMB program. Welcome, Sid!
Dominik Hoelper joins the lab as a graduate student through the IPiB program. Welcome, Dominik!
November
Peter Lewis is awarded the Mary Terese Hartzheim Young Investigator award!
October
The Lewis lab at the Wisconsin Institute for Discovery is up and running.